Publications


2018

Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan, Elizabeth Bilsland, Liisa van Vliet, Kevin Williams, Jack Feltham, Marta P. Carrasco, Wesley L. Fotoran, Eliana F. G. Cubillos, Gerhard Wunderlich, Morten Grøtli, Florian Holfelder, Victoria Jackson, Ross D. King, Stephen G. Oliver. Rep., 2018, 8, 1038; doi:10.1038/s41598-018-19549-x.

Fluorescent nucleobase analogues for base–base FRET in nucleic acids: synthesis, photophysics and applications, Mattias Bood, Sangamesh, Moa S. Wranne, Sarangamath, Morten Grøtli and Marcus L. Wilhelmsson. Beilstein J. Org. Chem. 2018, 14, 114–129.

2017

Network analyses identify liver-specific targets for treating liver diseases, Sunjae Lee, Cheng  Zhang , Zhengtao Liu, Martina Klevstig, Bani Mukhopadhyay, Mattias Bergentall, Resat Cinar, Marcus Ståhlman, Natasha Sikanic, Joshua K Park, Sumit Deshmukh, Azadeh M Harzandi, Tim Kuijpers, Morten Grøtli, Simon J Elsässer, Brian D Piening, Michael Snyder, Ulf Smith, Jens Nielsen, Fredrik Bäckhed, George Kunos, Mathias Uhlen, Jan Boren and  Adil Mardinoglu. Mol. Sys. Biol. 2017, 13, 938.

Improving economics of NASH/NAFLD treatment through the use of systems biology, Jim Bosley, Christofer Boren, Sunjae Lee, Morten Grøtli, Jens Nielsen, Jan Boren, Mathias Uhlen, Adil Mardinoglu. Drug. Disc. Today, 2017, 22, 1532-1538.

Towards compleate sequence flexibility of nuclic base analogue FRET, Moa S. Wranne, Anders Foller Larsen, Blaise Dumat, Mattias Bood, Afaf H. El Sagheer, Tom Brown, Henrik Gradén, Morten Grøtli and L. Marcus Wilhelmsson. J. Am. Chem. Soc. 2017, 139, 9271-9280.

On the Use of Diarylmaleimide Derivatives in Biological Contexts: An Investigation of the Photochromic Properties in Aqueous Solution, Cassandra Fleming, Patricia Remón, Shiming Li, Nadja Anita Simeth, Burkhard König, Morten Grøtli, Joakim Andréasson, Dyes Pigments, 2017, 137, 410–420.

2016

Flexibility is a Key Feature for Inhibition of the MDM2/p53 Protein-Protein Interaction by Cyclic Peptidomimetics, Emma Danelius, Mariell Pettersson, Matilda Bred, Jaeki Min, R. Kiplin Guy, Morten Grøtli, Mate Erdelyi, Org. Biomol. Chem. 2016, 14, 10386–10393.

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases, Marco Igor Valencia-Sánchez, Annia Rodríguez-Hernández, Ruben Ferreira, Hugo Aníbal Santamaría-Suárez, Marcelino Arciniega-Castro, Anne-Catherine Dock-Bregeon, Dino Moras, Brice Beinsteiner, Haydyn Mertens, Dmitri Svergun, Luis Brieba de Castro, Morten Grøtli, Alfredo Torres-Larios, J. Biol. Chem. 2016, 291, 14430–14446.

Defects in the Calcium-binding Region Drastically Affects the Cadherin-like Domains of RET Tyrosine Kinase, Chunxia Gao, Morten Grøtli, Leif A. Eriksson, Phys. Chem. Chem. Phys. 2016, 18, 8673–8681.

An Acido- and Photochromic Molecular Device that Mimics Triode Action, Patricia Remón, Shiming Li, Morten Grøtli, Uwe Pischel, Joakim Andréasson, Chem.Commun. 2016, 52, 4659–4662.

Chroman-4-one and Chromone Based Somatostatin β-Turn Mimetics, Maria Fridén-Saxin, Tina Seifert, Marcus Malo, Krystle da Silva Andersson, Nils Pemberton, Christine Dyrager, Annika Friberg, Kristian Dahlén, Erik A. A. Wallén, Morten Grøtli, Kristina Luthmana, Eur. J. Med.Chem. 2016, 114, 59–64.

7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a Fluorescence Turn-ON Probe for Single-strand DNA Binding Protein, Munefumi Tokugawa, Yoshiaki Masaki, Jan Christian Canggadibrata, Kazuhei Kaneko, Takashi Shiozawa, Takashi Kanamori, Morten Grøtli, L. Marcus Wilhelmsson, Mitsuo Sekine, Kohji Seioa, Chem.Commun. 2016, 52, 3809–3812.

Arsenic Directly Binds to and Activates the Yeast AP-1-like Transcription Factor Yap8, Nallani Kumar, Jianbo Yang, Jitesh Pillai, Swati Rawat, Carlos Solano, Abhay Kumar, Morten Grøtli, Timothy Stemmler, Barry Rosen, Markus Tamas, Mol. Cell. Biol. 2016, 36, 913–922.

2015

Design, Synthesis and Evaluation of Diketo-piperazines as Inhibitors of MDM2/p53, Mariell Pettersson, Maria Quant, Jaeki Min, Luigi Iconaru, Richard W. Kriwacki, M. Brett Waddell, R. Kiplin Guy, Kristina Luthman, Morten Grøtli, PLOS ONE, 2015, 10: e0137867.

A Caged RET Kinase Inhibitor and its Effect on Neuronal Development in Zebra Fish Embryogenesis, David Bliman, Jesper Nilsson, Petronella Kettunen, Joakim Andreasson, Morten Grøtli, Sci. Rep2015, 5, 13109.

Development of Bright Fluorescent Quadracyclic Adenine Analogues: TDDFT-calculation Supported Rational Design, Anders Foller Larsen, Blaise Dumat, Moa S. Wranne, Chris P. Lawson, Søren Preus, Mattias Bood, Henrik Gradén, L. Marcus Wilhelmsson, Morten Grøtli, Sci. Rep2015, 5, 12653.

Characterisation of Interactions and Pharmacophore Development for DFG-out Inhibitors to RET Tyrosine Kinase, Chunxia Gao, Morten Grøtli, Leif A. Eriksson, J.Mol.Model. 2015, 21: 167.

The unique characteristics of HOG pathway MAPKs in the extremely halotolerant Hortaea werneckii, Anja Kejžar, Matej Cibic, Morten Grøtli, Ana Plemenitaš, Metka Lenassi, FEMS Microbiol. Lett. 2015, 362, fnv046.

Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors, Rubén Ferreira, Jesper R. Nilsson, Carlos Solano, Joakim Andréasson, Morten Grøtli, Sci. Rep. 2015, 5, 09769.

8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction, Mariell Pettersson, David Bliman, Jimmy Jacobsson, Jesper Nilsson, Jaeki Min, Luigi Iconaru, R. Kiplin Guy, Richard W. Kriwacki, Joakim Andréasson, Morten Grøtli, PLOS ONE, 2015, 10: e0124423.

Second-Generation Fluorescent Quadracyclic Analogues: Environment Responsive Probes with Enhanced Brightness, Blaise Dumat, Mattias Bood, Moa Sandberg,  Christopher P. Lawson, Anders Foller Larsen, Søren Preus, Jens Streling,  Henrik Gradén,  Eric Wellner, Morten Grøtli, L. Marcus Wilhelmsson. Chem. Eur.J. 2015, 21, 4039–4048.

HwHog1 Kinase Activity is Crucial for Survival of Hortaea werneckii in Extremely Hyperosmolar Environments, Anja Kejžar, Morten Grøtli, Markus Tamas, Ana Plemenitaš, Metka Lenassi. Fungal Genet. Biol. 2015, 74, 45–58.

2014

Selective Inhibition of RET Mediated Cell Proliferation in vitro by the Kinase Inhibitor SPP86, John P Alao, Sona Michlikova, Peter Dinér, Morten Morten Grøtli, Per Sunnerhagen, BMC Cancer, 2014, 14, 853.

Chromo-pharmacophores: Photochromic diarylmaleimide inhibitors for sirtuins, Carolin Falenczyk, Matthias Schiedel, Natascha Kuzmanovic, Morten Grøtli, Wolfgang Sippl, Manfred Jung, Burkhard König, Chem. Sci2014, 5, 4794–4799.

Towards the Development of Chromone-based MEK1/2 Modulators, Itedale Namro Redwan, Christine Dyrager, Carlos Solano, Guillermo Fernández de Trocóniz, Laure Voisin, David Bliman, Sylvain Meloche, Morten Grøtli, Eur. J. Med. Chem. 2014, 85, 127–138.

Synthesis and Photophysical Characterization of New Fluorescent Triazole Adenine Analogues, Christopher P. Lawson, Anke Dierckx, Francois-Alexandre Miannay, Eric Wellner, L. Marcus Wilhelmsson, Morten Grøtli, Org. Biomol. Chem. 2014, 12, 5158–5167.

Application of a Peptide-based Assay to Characterize Inhibitors Targeting Protein Kinases from Yeast, Jenny Veide-Vilg, Sita Dahal, Thomas Ljungdahl, Morten Grøtli, Markus J. Tamás, Curr. Genetics. 2014, 60, 193–200.

8-Bromination of 2,6,9-Trisubstituted Purines with Pyridinium Tribromide, David Bliman, Mariell Pettersson, Mattias Bood, Morten Grøtli, Tetrahedron Lett2014, 55, 2929–2931.

Inhibition of MAPK Hog1 Results in Increased Hsp104 Aggregate Formation Probably Through Elevated Arsenite Influx into the Cells, an Approach with Numerous Potential Applications, Doryaneh Ahmadpour, Amin A. Banaeiyan1, Morten Grøtli, Martin Adiels, Caroline B. Adiels, Mattias Goksör, Am. J. Mol.Biol2014, 4, 59–91.

Evaluation of a Microfluidic Chamber for Single Yeast Cell Studies upon Multiple Environmental Changes, Charlotte Hamngren, Peter Dinér, Morten Grøtli, Mattias Goksör, Caroline Beck, Micromachines, 2014, 5, 81–96.

2013

Synthesis and Photophysical Characterization of 1- and 4-(Purinyl)triazoles, Itedale Namro Redwan, David Bliman, Munefumi Tokugawa, Christopher Lawson, Morten Grøtli, Tetrahedron, 2013, 69, 8857–8864.

2012

A Mild and Efficient Method for Activation and Recycling of Trityl Resins, Itedale Namro Redwan, Morten Grøtli, J. Org. Chem. 2012, 77, 7071–7075.

Proline-mediated Formation of Novel Chroman-4-one Tetrahydropyrimidines, Maria Fridén-Saxin, Tina Seifert, Lars Kristian Hansen, Morten Grøtli, Mate Erdelyi, Kristina Luthman, Tetrahedron, 2012, 68, 7035–7040.

Validation of Regulated Protein Phosphorylation Events in Yeast by Quantitative Mass Spectrometry Analysis of Purified Proteins, Wolfgang Reiter, Dorothea Anrather, Ilse Dohnal, Peter Pichler, Jiri Veis, Morten Grøtli, Francesc Posas, Gustav Ammerer, Protiomics, 2012, 12, 3030–3043.

Determination of Primary Sequence Specificity of Arabidopsis MAPKs MPK3 and MPK6 Leads to Identification of New Substrates, Carolin Sörensson, Marit Lenman, Simone Schopper, Jenny Veide-Vilg, Thomas Ljungdahl,  Morten Grøtli, Markus J. Tamás, Scott C. Peck, Erik Andreasson, Biochem. J. 2012, 446, 271–278.

Preparation of 3-Substituted-1-Isopropyl-1H-Pyrazolo[3,4-d]Pyrimidin-4-Amines as RET Kinase Inhibitors, Peter Dinér, John Patrick Alao, Johan Söderlund, Per Sunnerhagen, Morten Grøtli, J. Med. Chem. 2012, 55, 4872–4876.

Solid-Phase Synthesis of  5´-O-[N-(Acyl)sulfamoyl]Adenosine Derivatives, Itedale Namro Redwan, Hanna Jacobson Ingemyr, Thomas Ljungdahl, Christopher P. Lawson, Morten Grøtli, Eur. J. Org. Chem. 2012, 3665–3669.

Investigation, Optimization and Synthesis of Sulfamoyloxy-linked Aminoacyl-AMP Analogues, Itedale Namro Redwan, Thomas Ljungdahl, Morten Grøtli, Tetrahedron, 2012, 68, 1507–1514.

2011

Design and Synthesis of Chromone-based p38 MAP Kinase Inhibitors, Christine Dyrager, Linda Nilsson Möllers, Linda Karlsson Kjäll, John Patrick Alao, Peter Dinér, Fredrik K. Wallner, Per Sunnerhagen, Morten Grøtli, J. Med. Chem. 2011, 54, 7427–7431.

NMR-Based Substrate Analog Docking to Escherichia coli Peptidyl-tRNA Hydrolase, Laurent Giorgi, Pierre Plateau, Gavin O’Mahony, Caroline Aubard-Launay, Michel Fromant, Aurélien Thureau, Morten Grøtli, Sylvain Blanquet, François Bontems,  J. Mol. Biol. 2011, 412, 619–633.

Design, Synthesis and Characterization of a Highly Effective and Fast Acting Orthogonal Inhibitor for Analog-Sensitive (as) Kinases, Michael Klein, Montse Morillas, Alexandre Vendrell, Lars Brive, Marinella Gebbia, Guri Giaever, Corey Nislow Francesc Posas, Morten Grøtli, PLoS ONE 6(6): e20789.

Design, Synthesis, and Characterization of a Highly Effective Hog1 Inhibitor: A Powerful Tool for Analyzing MAP Kinase Signaling in Yeast, Peter Dinér, Jenny Veide Vilg, Jimmy Kjellén, Iwona Migdal, Teres Andersson, Marinella Gebbia, Guri Giaever, Corey Nislow, Stefan Hohmann, Robert Wysocki, Markus J. Tamás, Morten Grøtli, PLoS ONE, 6(5): e20012.

Inhibitors and Promoters of Tubulin Polymerization: Synthesis and Biological Evaluation of Chalcones and Related Dienones as Potential Anticancer Agents, Christine Dyrager, Maria Fridén-Saxin, Malin Wickström, Annika Friberg, Kristian Dahlén, Erik A. A. Wallén, Joachim Gullbo, Morten Grøtli, Kristina Luthman, Bioorg. Med. Chem. 2011, 19, 2659–2665.

Photophysical Characterization of Nucleic Acid Base-analogue AT Upon Incorporation into DNA, Anke Dierckx, Peter Dinér, Afaf El-Sagheer, Joshi Dhruval Kumar, Tom Brown, Morten Grøtli, Marcus L. Wilhelmsson, Nucl. Acids Res. 2011, 39, 4513–4524.

2010

Positional Scanning Peptide Libraries for Kinase Substrate Specificity Determinations: Straightforward and Reproducible Synthesis Using Pentafluorophenyl Esters, Thomas Ljungdahl, Jenny Veide, Fredrik Wallner, Markus Tamas, Morten Grøtli, J. Comb. Chem. 2010, 12, 733–742.

KHMDS Enhanced SmI2-mediated Reformatsky Type α-Cyanation, Tobias Ankner, Maria Fridén-Saxin, Nils Pemberton, Tina Seifert, Morten Grøtli, Kristina Luthman, Göran Hilmersson, Org. Lett. 2010, 12, 2210–2213.

Structural Influence on Radical Formation and Sensitizing Capacity of Alkylic Limonene Hydroperoxide Analogues in Allergic Contact Dermatitis, Staffan Johansson, Katarina Emilsson,  Morten Grøtli, Anna Börje, Chem. Res. Tox. 2010, 23, 677–688

2009

Synthesis of Chiral 1,4-Disubstituted-1,2,3-Triazole Derivatives from Amino Acids, Michael Klein, Karin Krainz, Itedale Namro Redwan, Peter Diner, Morten Grøtli, Molecules, 2009, 14, 5124–5143.

Solid Phase Peptide Synthesis in Water Using Microwave-Assisted Heating, Athanassios S. Galanis, Fernando Albericio, Morten Grøtli, Org. Lett. 2009, 11, 4488–4491.

Synthesis of 3-(1,2,3-triazol-1-yl)- and 3-(1,2,3-triazol-4-yl)- substituted Pyrazolo[3,4-d]pyrimidin-4-amines via Click Chemistry: Potential Inhibitors of the Plasmodium falciparum PfPK7 Protein Kinase, Michael Klein, Peter Dinér, Dominique Dorin-Semblat, Christian Doerig, Morten Grøtli, Org. Biomol. Chem.  2009, 7, 3421–3429.

2,6,8-Trisubstituted 3-Hydroxychromone Derivatives as Useful Probes for Fluorescence Microscopy in Living Cells, Christine Dyrager, Annika Friberg, Maria Saxin, Kristian Dahlén, Erik.A.A. Wallén, Karl Börjesson, Mathias Wilhelmsson, Bo Albinsson, Maria Smedh, Morten Grøtli, Kristina Luthman, Chem. Eur.J. 2009, 15, 9417–9423.

Synthesis and Photophysical Characterisation of Fluorescent 8-(1H-1,2,3-Triazol-4-yl)adenosine Derivatives, Christine Dyrager, Annelie Elf, Peter Diner, Karl Börjesson, Mathias Wilhelmsson, Bo Albinsson, Morten Grøtli, Eur. J. Org. Chem. 2009, 1515–1521.

Synthesis of 2-Alkyl-Substituted Chromone Derivatives Using Microwave Irradiation, Maria Fridén-Saxin, Nils Pemberton, Krystle da Silva Andersson, Christine Dyrager, Annika Friberg, Morten Grøtli, Kristina Luthman, J. Org. Chem. 2009, 74, 2755–2759.

Enhanced Microwave Assisted Method for On-Bead Disulfide Bond Formation. Synthesis of α-Conotoxin MII, Athanassios S. Galanis, Fernando Albericio, Morten Grøtli, Pep. Sci, 2009, 92, 23–34.

2008

Carbon and Oxygen Centred Radicals are Equally Important Haptens of Allylic Hydroperoxides in Allergic Contact Dermatitis, Staffan Johansson, Elena Giménez-Arnau, Morten Grøtli, Ann-Therese Karlberg, Anna Börje, Chem. Res. Tox. 2008, 21, 1536–1547.

Synthesis and Photophysical Properties of Novel Cyclonucleosides – Substituent Effects on Fluorescence Emission, Gavin O’Mahony, Eleonor Ehrman, Morten Grøtli, Tetrahedron, 2008, 7151–7158.

Synthesis of 2’-([1,2,3]Triazol-l-yl)-2’-deoxyadenosines, Gavin O’Mahony, Sara Svensson, Andreas Sundren, Morten Grøtli, Nucleosides, Nucleotides & Nucleic Acids, 2008, 449–459.

2007

Microwave Assisted Synthesis of Spiro-2,5-Diketopiperazines, Fariba Jam, Marcus Tullberg, Kristina Luthman, Morten Grøtli, Tetrahedron, 2007, 63, 9881–9889.

A Practical Synthesis of 2’-Aminoacylamino-2’-Deoxyadenosines, Gavin O’Mahony, Andreas Sundgren, Sara Svensson, Morten Grøtli, Tetrahedron, 2007, 63, 6901–6908.

Synthesis of 3-Aminomethyl-2-aryl-8-bromo-6-chloro-chromones, Erik A. A. Wallén, Kristian Dahlén, Morten Grøtli, Kristina Luthman, Org. Lett. 2007, 9, 389–391.

Synthesis of Functionalized, Unsymmetrical 1,3,4,6-Tetrasubstituted 2,5-Diketopiperazines, Marcus Tullberg, Morten Grøtli, Kristina Luthman, J.Org.Chem. 2007, 72,  195–199.

2006

Microwave-Assisted Solid-Phase Synthesis of 2,5-Diketopiperazines: Solvent and Resin Dependence, Marcus Tullberg, Kristina Luthman, Morten  Grøtli,  J. Comb. Chem. 2006, 8, 915–922.

Synthesis of 2,3,6,8-Tetrasubstituted Chromone Scaffolds, Kristian Dahlén, Erik A. A. Wallén, Morten Grøtli, Kristina Luthman, J.Org.Chem. 2006, 71, 6863–6871.

Microwave-Assisted Synthesis of the Schöllkopf Chiral Auxiliaries: (3S)- and (3R)-3,6-dihydro-2,5-diethoxy-3-isopropyl-pyrazine, Anna-Carin Carlsson, Fariba Jam, Marcus Tullberg, Åke Pilotti, Panos Ioannidis, Kristina Luthman, Morten Grøtli, Tetrahedron Lett. 2006, 47, 5199–5201.

Efficient Synthesis of 2,5-Diketopiperazines using Microwave Assisted Heating, Marcus Tullberg, Morten Grøtli, Kristina Luthman, Tetrahedron, 2006, 62, 7484–7491.

Efficient Synthesis of 3,6,8-Trisubstituted Flavones, Kristian Dahlén, Morten Grøtli, Kristina Luthman, SynLett. 2006, 6, 897–900.

Role of the Subunit Composition of Central Nicotinic Acetylcholine Receptors for the Stimulatory and Dopamine-enhancing Effects of Ethanol, Elisabet Jerlhag, Morten Grøtli, Kristina Luthman, Lennart Svensson, Jörgen A. Engel,  Alcohol and Alcoholism, 200641, 486–493

Discovery of New Classes of Brugia malayi Asparaginyl tRNA Synthetase Inhibitors and Relating Selectivity to Conformational Change, Sai Chetan K. Sukuru1, Thibaut Crepin, Youli Milev, Liesl C. Marsh, Jonathan B. Hill, Regan J.Anderson, Jonathan C. Morris, Anjali Rohatgi1, Gavin O’Mahony, Morten Grøtli, Franck Danel, Malcolm G.P. Page, Michael Härtlein, Stephen Cusack, Michael A. Kron, Leslie A. Kuhn,  J. Comp.-Aided Mol. Design, 2006, 20, 159–178.

2005

Synthesis of Adenosine-based Fluorosides Containing a Novel Heterocyclic Ring System, Gavin O’Mahony, Eleonor Ehrman, Morten Grøtli, Tetrahedron Lett. 2005, 46, 6745–6748.

2004

The Biotin Repressor: Modulation of Allostery by Corepressor Analogs, Patrick H. Brown, John E. Cronan, Morten Grøtli, Dorothy Beckett, J. Mol. Biol. 2004, 337, 857–869.

2003

Strategies for Antifilarial Drug Development, M.A. Kron, L.A. Kuhn, P.C. Sanschagrin, M. Hartlein, M. Grøtli,  S. Cusack, J. Parasitol2003, 89 (Suppl.), S226–S235.

Structural and Mechanistic Basis of Pre-and Post-transfer Editing by Leucyl-tRNA Synthetase, Tommie L. Lincecum, Michael Tukalo, Anna Yaremchuk, Richard S. Mursinna, Amy M. Williams, Brian S. Sproat, Wedy Van Den Eynde, Andreas Link, Serge Van Calenbergh, Morten Grøtli, Susan A. Martinis, Stephen Cusack, Mol. Cell. 2003, 11, 951–963.

2002

SPOCC-194, a New High Functional Group Density PEG-Based Resin for Solid-Phase Organic Synthesis, Les P. Miranda, William D. Lubell, Koen M. Halkes, Thomas Groth, Morten Grøtli, Jörg Rademann, Charlotte H. Gotfredsen, Morten Meldal, J. Comb. Chem. 2002, 4, 523–529.

Palladium on Carbon Encapsulated in POEPOP1500- A Resin Supported Catalyst for Hydrogenation Reactions, Anita Janson, Morten Grøtli, Koen M Halkes, Morten Meldal, Org. Lett. 2002, 4, 27–30.

2001

A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Prolyl-tRNA Synthetase, Anna Yarmchuk, Mikhail Tukalo, Morten Grøtli, Stephen Cusack, J. Mol. Biol. 2001, 309, 1016–1029.

Diffusion of Reagents in Macrobeads, Thomas Groth, Morten Grøtli, Morten Meldal, J. Comb. Chem. 2001, 3, 461–468.

Solid-Phase Glycosylation of Peptide Templates and On-Bead MAS-NMR Analysis: Perspectives for Glycopeptide Libraries, Koen .M. Halkes, Charlotte H. Gotfredsen, Morten Grøtli, Les P. Miranda, Jens Ø. Duus, Morten Meldal, Chem. Eur.J. 2001, 7, 3584–3591.

Surfactant Mediated Cationic and Anionic Suspension Polymerization of PEG-based Resins in Silicon Oil; Beaded SPOCC 1500 and POEPOP 1500, Morten Grøtli,  Jörg Rademan, Thomas Groth, William Lubell, Les Miranda, Morten Meldal, J. Comb. Chem. 2001, 3, 28–33.

2000

HYDRA: A Novel Hydroxyl and Amine Functionalised Resin Synthesised by Reductive Amination of PEG Aldehyde and a Polyamine, Thomas Groth, Morten Grøtli, William Lubell, Les Miranda, Morten Meldal, J. Chem. Soc. Perkin Trans. 12000, 4258–4264.

Secondary Structure Prediction and in vitro Accessibility of mRNA as Tools in the Selection of Target Sites for Ribozymes, Mohammed Amarzguioui, Gaute Brede, Eshrat Babaie, Morten Grøtli, Brian Sproat, Hans Prydz, Nucleic Acid Res. 2000, 28, 4113–4124.

Crystallization and Preliminary Crystallographic Analysis of Thermus thermophilus Leucyl-tRNA Synthetase and its Complexes with Leucine and Non-hydrolysable Leucyl Adenylate Analogue, Anna Yarmchuk, Stephen Cusack, Olga Gudzera, Morten Grøtli, Mikhail Tukalo, Acta Crystallogr D Biol Crystallogr. 2000, 56, 667–669.

Towards Peptide Isoster Libraries: Aqueous Aldol Reactions on Hydrophilic Solid Supports, Anette Graven, Morten Grøtli, Morten Meldal, J. Chem. Soc. Perkin Trans. 1 2000, 955–962.

Physical Properties of Polyethylene Glycol (PEG)-based Resins for Combinatorial Solid Phase Organic Chemistry: A Comparison of PEG Cross-Linked and PEG Grafted Resins, Morten Grøtli, Charlotte H. Gotfredsen, Jörg Rademann, Jens Buchardt, Anthony J. Clark, Jens Ø. Duus, Morten Meldal, J. Comb. Chem. 2000, 2, 108–119.

Single-bead Structure Elucidation. Requirements for Analysis of Combinatorial Solid-phase Libraries by Nanoprobe MAS-NMR Spectroscopy, Charlotte H. Gotfredsen, Morten Grøtli, Marianne Willert, Morten Meldal, Jens Ø. Duus, J. Chem. Soc. Perkin Trans. 1 2000, 1167–1171.

1999

2′-O-(Carbamoylmethyl)oligoribonucleotides, Morten Grøtli, Barbro Beijer, Brian Sproat, Tetrahedron, 1999, 55, 4299–4314.

SPOCC: A Resin for Solid Phase Organic Chemistry and Enzymatic Reactions on Solid Phase, Jörg Rademann, Morten Grøtli, Morten Meldal, Klaus Bock, J. Am. Chem. Soc1999, 121, 5459–5466.

1998

The Crystal Structure of Asparaginyl-tRNA Synthetase from Thermus Thermophilus and its Complexes with ATP and Asparaginyl-adenylate: the Mechanism of Discrimination between Asparagine and Aspartic acid, Carmen Berthet-Colominas, Laurence Seignovert, Michael Härtlein, Morten Grøtli, Stephen Cusack, Reuben Leberman, EMBO Journal, 1998, 17, 2947–2960.

2’-O-Propargyl Oligonucleotides: Synthesis and Hybridisation, Morten Grøtli, Mark Douglas, Ramon Eritja, Brian S. Sproat, Tetrahedron, 1998, 54, 5899–5914.

1997

Preparation of Oligonucleotides Containing Non-Natural Base Analogs, Ramon Eritja, Vivian Adam, Anna Aviñó, Antonio R. Diaz, Carma Fàbrega, Elisenda Ferrer, Morten Grøtli, Ramon Güimil Garciá, Mechtild Hofmann, Victor E. Marquez, Marten Wiersma, Nucleosides & Nucleotides, 1997, 16, 697–702.

Solid-phase Synthesis of Branched RNA and Branched DNA/RNA Chimeras, Morten Grøtli, Ramon Eritja, Brian Sproat, Tetrahedron, 1997, 11317–11346.

Protection of the Guanine Residue During Synthesis of 2’-O-Alkylguanosine Derivatives, Morten Grøtli, Mark Douglas, Barbro Beijer, Ramon Gümil Garciá, Ramon Eritja, Brian Sproat, J. Chem. Soc. Perkin Trans. 1 1997, 2779–2788.

A Simple Method for the Synthesis of 2’-O-Alkyl Guanosine Derivatives, Morten Grøtli, Mark Douglas, Barbro Beijer, Ramon Eritja and Brian S. Sproat, BioMed. Chem. Lett. 1997, 7, 425–428.

1996

Ether, Carbonate and Urethane Deoxynucleoside Derivatives as Prodrugs, Kristin Hammer, Jostein Hatlelid, Morten Grøtli, Joseph Arukwe, Jo Klavness, Frode Rise, Kjell Undheim, Acta Chem. Scand. 1996, 609–622.

1995

A Universal Solid-phase Synthesis of Branched Oligonucleotides, Morten Grøtli, Brian S. Sproat, J. Chem. Soc., Chem. Commun. 1995, 495–497.

Synthesis of 2’-Allyl-2’Deoxynucleosides by Radical Reactions, Morten Grøtli, Kjell Undheim, Acta Chem. Scand. 1995, 49, 217–224.

1994

Simplified and Cost Effective Synthesis of Fully Protected Phosphoramidite Monomers Suitable for the Assembly of Oligo(2’-O-Allylribonucleotides), Barbro Beijer, Morten Grøtli, Mark E. Douglas, Brian S. Sproat, Nucleosides & Nucleotides, 1994, 13, 1905–1927.

Novel Solid-phase Synthesis of Branched Oligoribonucleotides, including a Substrate for the RNA Debranching Enzyme, Brian S. Sproat, Barbro Beijer, Morten Grøtli, Ursula Ryder, Kenneth L. Morrand, Angus I. Lamond, J. Chem. Soc. Perkin Trans. 1 1994, 419–432.