Yongjin Xu

PhD student

yongjin.xu@gu.se

EDUCATION

2012–2015          M.A. in Med. Chem.
                             Sichuan University, China
2008–2012          B.A. in Pharmacy
                             Sichuan University, China

RESEARCH INTERESTS

I’m interested in photopharmacology. Presently, I focus on developing kinase inhibitors by inserting photoresponsive units into the chemical structures. These switching units will allow for the use of light as an external control element for pharmacological activity with high spatiotemporal precision, resulting in in vivo activation/deactivation. Results from these studies will have implications for future drug development for treatment of neurodegenerative diseases, e.g. Alzheimer’s disease.

PUBLICATIONS

1,4-Hydroiodination of Dienyl Alcohols with TMSI To Form Homoallylic Alcohols Contain a Multisubstituted Z-Alkene and Application to Prins CyclizationJ. Xu; Z. P. Yin; X. L. Lin, Z. B. Gan, Y. Y. He, L. Gao, and Z. L Song, Org. Lett. 2015, 17, 1846–1849.

Total Synthesis of (−)-Exiguolide via Organosilane-Based Strategy, Z. Li; H. M. Xie; Z. G. Zhang; Y. J. Xu; L. Gao; Z. L. Song, Chem. Commun2015, 51, 8484–8487

[1,5]-Brook rearrangement: an overlooked but valuable silyl migration to synthesize configurationally defined vinylsilane. The unique steric and electronic effects of geminal bis(silane), Gao, J. Lu, Z. L. Song, X. L. Lin, Y. J. Xu and Z. P. Yin, Chem. Commun. 2013, 49, 8961–8963

Identification and content determination of Tibetan medicine Syzygium jambos (in Chinese), Zheng; S. Wang; Y. J. Xu; X. Chen, West China Journal of Pharmaceutical Sciences. 2011, 26, 508–509.