2013–2016 PhD studies
Charles Sturt University, Orange NSW, Australia
2009–2011 MPhil in Med. Chem.
School of Pharmacy, University of Sydney, Sydney, Australia
2010 Registered pharmacist in Australia
Pharmacy Board of NSW examination
2005 Bachelor degree in Pharmaceutical Sciences
Ain Shams University, Egypt
Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N’-(methoxyphenylalkyl)-piperazine σ₁ receptor ligands, Moussa I.A, Banister S.D, Akladios F.N, Chua S.W, Kassiou. M, Bioorg. Med. Chem. Lett. 2011, 21, 5707–5710.
Design and synthesis of novel inhibitors of human kynurenine aminotransferase-I, F. N. Akladios, N. A. Nadvi, J. Park, J. R. Hanrahan, V. Kapoor, M. D. Gorrell, W. B. Church, Bioorg. Med. Chem. Lett. 2012, 22, 1579–1581.
Selective induction of oxidative stress in cancer cells via synergistic combinations of agents targeting redox homeostasis, F.N. Akladios , S.D. Andrew, C. J. Parkinson, Bioorg. Med. Chem. 2015, 23, 3097–3104.
Improved Cytotoxicity of Pyridyl- substituted Thiosemicarbazones Against MCF-7 when used as Metal Ionophores, F.N Akladios , S.D. Andrew, C. J. Parkinson, BioMetals 2016, 29, 157–170.
Increased generation of intracellular reactive oxygen species initiates selective cytotoxicity against the MCF-7 cell line resultant from redox active combination therapy using copper-thiosemicarbazone complexes, F.N. Akladios, S. D. Andrew, C. J. Parkinson, J. Biol. Inorg. Chem. 2016, 21, 407–419.
Investigation of cytotoxic implication of different metal chelators against Melanoma and different approaches to improve the cytotoxicity profiles of metal coordinating agents, F.N. Akladios, S. D. Andrew, C. J. Parkinson, BioMetals, 2016, 29, 789–805.
Cytotoxic Activity of Expanded Coordination Bis-Thiosemicarbazones and Copper Complexes Thereof, F. N. Akladios, S. D. Andrew, C. J. Parkinson, J. Biol. Inorg. Chem. 2016, 21, 931–944.